Giovanna Delogu
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Giovanna Delogu |
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Address: | Dip. di Scienze della Vita e dell’Ambiente Via Ospedale, 72 09127 CAGLIARI |
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Phone: | +39 070 6758566 | |
Fax: | +39-070 6758675 | |
Email: | delogu@unica.it |
Curriculum vitae
Dr. Giovanna Delogu, holds a degree in Pharmacy at the University of Cagliari in July of 1992 discussing an experimental thesis entitled “Sintesi e proprietà di una nuova classe di podandi”.
In November 1992, she won a scholarship “Ph.D. in Chimica del Farmaco” Cyclo-VIII at the Drug Chemical Technologic Department of the Pharmacy Faculty of the University of Cagliari.
In October 1996 she received the title of Doctor of research in Chemistry of Drug in the area of organic chemistry, presenting a written work entitled: “Derivati benzonaftiridinici: sintesi e studio della loro attività biologica”. Since February 1996 is Researchers at the Drug Chemical Technologic Department of the Faculty of Pharmacy of the University of Cagliari for Scientific Field disciplinary CHIM/06-Organic Chemistry and still holds that role.
Lines of research
- Progettazione e sintesi di nuovi derivati ibridi cumarina-resveratrolo combinando le proprietà attribuite ad entrambi i frammenti strutturali.
- Sintesi, identificazione e caratterizzazione strutturale di prodotti secondari potenzialmente attivi nella sintesi di 2-arilbenzofurani mediante GC/MS e spettrometria di massa Tandem.
- Progettazione e sintesi di 2-fenilbenzofurani (che incorporano nella loro struttura il nucleo del resveratrolo) e studio della loro attività inibitoria nei confronti della tirosinasi.
- Progettazione e sintesi di 3-fenilcumarine e 4-idrossi-3-fenilcumarine e studio della loro attività inibitoria nei confronti delle monoaminossidasi.
- Caratterizzazione strutturale dei composti sintetizzati e studio dell’attività in diversi campi farmacologici.
Publications from 2008 to 2013
- E.Quezada, G.Delogu, D.Vina, L.Santana, C.Picciau, G.Podda and E.Uriarte
Synthesis and Complete Assignment of the 1H and 13C NMR Signals of Oxopyrancoumarin And Oxofuropyrancoumarin Derivatives
Magnetic Resonance in Chemistry 2008, 46, 7, 701-705; ISSN: 07491581; DOI: 10.1002/mrc.2223 - G.Ferino, H.Gonzalez-Diaz, G.Delogu, G.Podda, E.Uriarte
Using Spectral Moments of Spiral Networks Based on Psa/Mass Spectra Outcomes to Derive Quantitative Proteome-Disease Relationships (Qpdrs) And Predicting Prostate Cancer
Biochemical Biophysical Research Communications (BBRC) 2008, 372, 2, 320-325; ISSN: 0006291X; DOI: 10.1016/j.bbrc.2008.05.071 - E. Quezada, G. Delogu, D. Viña, L. Santana, G. Podda, M. Joao Matos, C. Picciau
Synthesis of Regio-Isomeric Functionalized Benzodifurans and Angelicins
Helvetica Chimica Acta 2009, 92, 7, 1309-1314; ISSN: 0018019X; DOI: 10.1002/hlca.200800421 - A. Fais, M. Corda, B. Era, M. B. Fadda, M. J. Matos, E. Quezada, L. Santana, C. Picciau, G. Podda, G. Delogu
Tyrosinase Inhibitor Activity of the Coumarin-Resveratrol Hybrids
Molecules 2009, 14, 7, 2514-2520; ISSN: 14203049; DOI: 10.3390/molecules14072514 - M. J. Matos, D. Viña, E. Quezada, C. Picciau, G.Delogu, F. Orallo, L. Santana, E. Uriarte
A New Series of 3-Phenylcoumarins as Potent and Selective Mao-B Inhibitors Bioorganic & Medicinal Chemistry Letters 2009, 19, 12, 3268-3270; ISSN: 0960894X; DOI: 10.1016/j.bmcl.2009.04.085 - S.Vazquez, E.Quezada, S.Vilar, G.Delogu, L.Santana, A.Fais, B.Era
Hydroxy Derivatives of 3-Arylcoumarins as Tyrosinase Inhibitors
Drugs of future-frontiers in Medicinal Chemistry: Emerging Targets, Novel Candidates and innovative strategies-Barcelona 4-6 october 2009
DRUGS OF THE FUTURE 2009, 34, 188-188 Published: Oct 2009 ISSN: 0377-8282 - Elías Quezada, Giovanna Delogu, Carmen Picciau, Lourdes Santana, Gianni Podda, Fernanda Borges, Verónica García-Morales, Dolores Viña and Francisco Orallo
Synthesis and Vasorelaxant and Platelet Antiaggregatory Activities of a New Series of 6-Halo-3-Phenylcoumarins
Molecules 2010, 15, 1, 270-279; ISSN: 14203049; DOI: 10.3390/molecules15010270 - E. Quezada, D. Viña, G. Delogu, F. Borges, L. Santana, and E. Uriarte
Synthesis of Carbocyclic Pyrimidine Nucleosides Using the Mitsunobu Reaction: O2– Vs. N1-Alkylation
Helvetica Chimica Acta 2010, 93, 2, 309-313; ISSN: 0018019X; DOI: 10.1002/hlca.200900242 - M. J. Matos, Giovanna Delogu, Gianni Podda, Lourdes Santana, , E. Uriarte
Regioselective Synthesis of Bromo-Substituted 3-Arylcoumarins
Synthesis 2010, 16, art. no. T05010SS, 2763-2766; ISSN: 00397881; DOI: 10.1055/s-0029-1218835 - G. Delogu, G. Podda, M. Corda, M. B. Fadda, A. Fais, B. Era.
Synthesis and Biological Evaluation of a Novel Series of Bis-Salicylaldehydes as Mushroom Tyrosinase Inhibitors
Bioorganic & Medicinal Chemistry Letters 2010, 20, 20, 6138-6140; ISSN: 0960894X; DOI: 10.1016/j.bmcl.2010.08.018 - A.Fais, S.Utzeri, G.Delogu, G.Podda, M.Corda, M.B.Fadda, B.Era
Tyrosinase Inhibitor Activity of a New Series of Bis-Salicylaldehyde
Journal of Biological Research 2010, 83, 72, 1826-8838 ISSN (Short communication) - Giovanna Delogu, Carmen Picciau, Giulio Ferino, Elías Quezada, Gianni Podda,
Eugenio Uriarte, Dolores Viña Synthesis, Human Monoamaine Oxidase Inhibitory and Molecular Docking Studies of 3-Heteroarylcoumarins Derivatives
European Journal of Medicinal Chemistry 2011, 46, 4, 1147-1152; ISSN: 02235234;DOI: 10.1016/j.ejmech.2011.01.033 - Maria João Matos, Lourdes Santana, Eugenio Uriarte, Giovanna Delogu, Antonella Fais, Maria Benedetta Fadda, Benedetta Era and Marcella Corda
New Halogenated Phenylcoumarins as Tyrosinase Inhibitors
Bioorganic & Medicinal Chemistry Letters 2011, 21, 3342–3345; ISSN: 0960894X; DOI: 10.1016/j.bmcl.2011.11.020 - Silvia Serra, Giulio Ferino, Maria João Matos, Saleta Vazquez-Rodriguez, Giovanna Delogu, Dolores Viña, Enzo Cadoni, Lourdes Santana and Eugenio Uriarte. Hydroxycoumarins as Selective Mao-B Inhibitors
Bioorganic & Medicinal Chemistry Letters 2012, 22, 1, 258-261; ISSN: 0960894X; DOI: 10.1016/j.bmcl.2011.11.020 - Fernanda Pérez-Cruz, Silvia Serra ,Giovanna Delogu, Michel Lapier, Juan Diego Maya, Claudio Olea-Azar, Lourdes Santana, Eugenio Uriarte
Antitrypanosomal and Antioxidant Properties of 4-Hydroxycoumarin Derivatives Bioorganic & Medicinal Chemistry Letters 2012, 22, 17, 5569-5573; ISSN: 0960894X; DOI: 10.1016/j.bmcl.2012.07.013 - Silvia Serra, Andrea Chicca, Giovanna Delogu, Saleta Vázquez-Rodríguez, Lourdes Santana , Eugenio Uriarte, Laura Casu, Jürg Gertsch
Synthesis and Cytotoxic Activity of non-Naturally Substituted 4-Oxycoumarin Derivatives
Bioorganic & Medicinal Chemistry Letters 2012, 22, 18, 5791-5794; ISSN: 0960894X; DOI: 10.1016/j.bmcl.2012.07.099 - Dolores Viña, Silvia Serra, Manuel Lamela and Giovanna Delogu
Herbal Natural Products as a Source of Monoamine Oxidase Inhibitors: A review
Current Topics in Medicinal Chemistry 2012, 12, 20, 2131-2144; ISSN: 15680266 - Giulio Ferino, Enzo Cadoni, Maria João Matos, Elias Quezada, Eugenio Uriarte, Lourdes Santana, Santiago Vilar, Nicholas P. Tatonetti, Matilde Yáñez, Dolores Viña, Carmen Picciau, Silvia Serra, Giovanna Delogu
MAO Inhibitory Activity of 2-Arylbenzofurans versus 3-Arylcoumarins: Synthesis, in vitro Study, and Docking Calculations
ChemMedChem 2013, 8, 6, 956-966; ISSN: 18607179; DOI: 10.1002/cmdc.201300048
International collaborations
Prof. Eugenio Uriate e Prof. Lourdes Santana – Departamento de Quimica Organica – Facultade de Farmacia