Cabiddu Claudia
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claudia.cabiddu@unica.it |
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Curriculum vitae
Claudia graduated with honours in Biology at the University of Cagliari on February 26th 2019, discussing a bachelor thesis titled “Use of microdialysis applied to metabolomics studies for the analysis of neurochemical variations in specific brain areas”, under the supervision of Prof. Laura Dazzi.
She graduated with honours in Cellular and Molecular Biology at the University of Cagliari on November 17th 2021, discussing a master thesis titled “Study of the effect of SARS-CoV-2 protein N on the innate immune response such as possible pharmacological target”, under the supervision of Prof. Enzo Tramontano. During her internship in the laboratory of Molecular Virology, she worked on the luciferase assay. In particular, this assay was used to evaluate the inhibitory action of the N protein of SARS-CoV-2 on the interferon system, specifically on the production cascade mediated by the promoter implicated in the synthesis of IFN, or on the cascade activated by the interferon signal mediated by the promoter ISRE.
Thanks to the Erasmus+ Traineeship Programme, after the graduation she spent 3 months (01/03/22 – 31/05/22) in Leuven at the Laboratory of Virology and Chemotherapy – Rega Institute-, where she worked on Human Cytomegalovirus (HCMV) and Herpes Simplex Virus (HSV) type 1 and 2, members of the human herpesviruses and she used CRISPR/Cas9 to introduce different mutations to study drug-resistance when the virus is put under antiviral pressure.
In December 2022 she won a seven-months research fellowship “Isolation of cellular populations from peripheral blood of Multiple Sclerosis patients and healthy controls, RNA extraction, and next generation sequencing” at the Department of Life and Environmental Sciences (Supervisor: Doc. Nicole Grandi).
Subsequently, in July 2023, she won another research fellowship “Implementation of an omics platform for the study of the cellular responses to viral infections” at the Department of Life and Environmental Sciences (Supervisor: Prof. Enzo Tramontano).
She is currently attending the XXXIX cycle of PhD in Life, Environmental and Drugs Sciences (Biomedical Curriculum) under the supervision of Doc. Nicole Grandi with a project focused on the HERV (Human Endogenous Retrovirus) and their protein expression in Drosophila melanogaster model.