Lisa Sequeira completed the Degree and the Master’s Degree in Chemistry at the Faculty of Sciences, University of Porto, Portugal, in the years 2011 and 2013, respectively. Her thesis was performed in her second year of the Master and was entitled “Design and synthesis of novel antioxidants based on natural scaffolds” under the supervision of Professor Fernanda Borges.
After the successful conclusion of her MSc, she was integrated in the FCT funded project entitled “Polymorphism in Pharmaceuticals: New Insights From NMR Crystallography” with a research grant, which started in 2014, in CICECO – Aveiro Institute of Materials, Department of Chemistry of the University of Aveiro, Portugal. After this grant, she stayed in the same institution with two more grants until 2017. In 2017 she was integrated in LEPABE in the Department of Chemical Engineering of the University of Porto, Portugal in the project “PowerFlow” with a research grant for six months. In 2018, she started working again under the supervision of Prof. Fernanda Borges with a research grant.
Lisa joined the XXXIV Cycle PhD program in Life, Environmental and Drug Sciences, drug sciences curriculum, at University of Cagliari in 2018 under the supervision of Professor Elias Maccioni and is currently working on a project focused on the design and synthesis of chromones, coumarins and non-nitrocatechol COMT inhibitors with potential biological activity.
-Distinto, S.; Meleddu, R.; Ortuso, F.; Cottiglia, F.; Deplano, S.; Sequeira, L.; Melis, C.; Fois, B.; Angeli, A.; Capasso, C.; Angius, R.; Alcaro, S.; Supuran, C. T.; Maccioni, E., Exploring new structural features of the 4- (3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino benzenesulph onamide scaffold for the inhibition of human carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 2019, 34 (1), 1526-1533.
-Cendak, T.; Sequeira, L.; Sardo, M.; Valente, A.; Pinto, M. L.; Mafra, L., Detecting Proton Transfer in CO2 Species Chemisorbed on Amine-Modified Mesoporous Silicas by Using (CNMR)-C-13 Chemical Shift Anisotropy and Smart Control of Amine Surface Density. Chemistry-a European Journal 2018, 24 (40), 10136-10145.
-Oliveira, C.; Cagide, F.; Teixeira, J.; Amorim, R.; Sequeira, L.; Mesiti, F.; Silva, T.; Garrido, J.; Remiao, F.; Vilar, S.; Uriarte, E.; Oliveira, P. J.; Borges, F., Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors. Frontiers in Chemistry 2018, 6.