Tiziana Cabras

 
Tiziana Cabras

Tiziana Cabras
Address: Dep. of Life and Environmental Sciences, Biomedical section,
University of Cagliari, Campus of Monserrato, S.S. 554 bivio per Sestu,
Phone: +39-070/6754505, +39-070/6754500
Fax: +39-070/6754523
Email: tcabras@unica.it

Curriculum vitae

June 22, 1975, Cagliari (Italy).
2001 Graduate in Biology at Cagliari University.
2004 Ph.D in “Human, Molecular and Animal Biology” -Cagliari University-.
2004-2008 Research activity principally on salivary proteomics made at the Cagliari University. Acquisition of knowledge and skills on mass spectrometry and proteomics techniques by stages at the Biochemistry and Clinical Biochemistry Institute of the Rome Catholic University and specialized courses.
2008 Research fellow of Biochemistry in the Pharmacy Faculty -Cagliari University- and actually at the Department of Life and Environmental Sciences, Biology and Pharmacy Faculty. From 2009 Biochemistry teaching in Toxicology Course.
SIB and ITPA society affiliations.

Lines of research

Area of expertise interests the application of advanced mass spectrometry techniques (HPLC-ESI-IT MS, MALDI-TOF-MS, LTQ-Orbitrap) to structural and functional proteomic of biofluids, cells and tissues for the disease biomarkers characterization.  Principal investigations are carried on human saliva by Top-Down MS approaches. These studies established the different sources of the major salivary proteins and the qualitative/quantitative changes in relation to different physiological states (age, taste sensitivity). Drastic variations in salivary proteome occur during the foetal development and after birth in function of the growth. A link between basic proline-rich proteins and the sensitivity to bitter taste was evidenced. These studies represent the base for comparative studies including pathological conditions, localized in the oral cavity and systemic. Proteomic and peptidomic changes have been evidenced in different pathologies studied (Autism disorder, Type I Diabetes, Down Syndrome, Sjogren’s syndrome, oral cavity tumors, Schizophrenia and Immunological pathologies) and in other under study (Wilson disease, and Immunological pathologies). These changes reflect the role of S100 proteins, thymosin beta4, alfa-defensins, histatins, acidic proline-ric proteins, statherin, and of some enzyme pathways in the disease. Proteomics/ peptidomics studies on tissues extracts, currently underway, combined with immunohistochemical ones, are addressed to characterize potential biomarkers of colo-rectal cancer in human, and in particular to understand the role of thymosins in the epithelial-mesenchymal transition of the tumor. Such as biochemical/immunoistochemical studies investigate the role of thymosin beta4 in the development of embrional tissues.
Structural characterization of new salivary peptides with potential biological activity, is performed in human, pig and rat saliva.

Website

http://people.unica.it/tizianacabras/

Publications from 2008 to 2015

  1. Messana I, Cabras T, Iavarone F, Manconi B, Huang L, Martelli C, Olianas A, Sanna MT, Pisano E, Sanna M, Arba M, D’Alessandro A, Desiderio C, Vitali A, Pirolli D, Tirone C, Lio A, Vento G, Romagnoli C, Cordaro M, Manni A, Gallenzi P, Fiorita A, Scarano E, Calò L, Passali GC, Picciotti PM, Paludetti G, Fanos V, Faa G, Castagnola M. Chrono-proteomics of human saliva: variations of the salivary proteome during human development. J Proteome Res. 2015; 14:1666-77 (I.F. 5.001; Q1)
  2. Tian N, Messana I, Leffler DA, Kelly CP, Hansen J, Cabras T, D’Alessandro A, Schuppan D, Castagnola M, Helmerhorst EJ. Salivary proline-rich proteins and gluten: Do structural similarities suggest a role in celiac disease? Proteomics Clin Appl. 2015 Feb 27. doi: 10.1002/prca.201400170. [Epub ahead of print] ( I.F.2.683; Q2)
  3. Sanna M, Firinu D, Manconi PE, Pisanu M, Murgia G, Piras V, Castagnola M, Messana I, del Giacco SR, Cabras T. The Salivary Proteome Profile in Patients Affected by SAPHO Syndrome characterized by a top-down RP-HPLC-ESI-MS platform. Molecular BioSystems. 2015; 11:1552-62. (I.F. 3.183; Q2)
  4. Cabras T, Iavarone F, Martelli C, Delfino D, Rossetti DV, Inserra I, Manconi B, Desiderio C, Messana I, Hannappel E, Faa G, Castagnola M. High-Resolution Mass spectrometry for Thymosins Detection and Characterization. Expert Opin Biol Ther. 2015; Early Online:1-11. Doi: 10.1517/14712598.2015. In press. (I.F. 3.653; Q1)
  5. Piludu M, Piras M, Pichiri G, Coni P, Orrù G, Cabras T, Messana I, Faa G, Castagnola M. Thymosin Beta 4 may translocate from the cytoplasm in to the nucleus in HepG2 cells following serum starvation. An ultrastructural study. PLoS One. 2015; 10:e0119642 (I.F. 3.534; Q1)
  6. Cabras T, Iavarone F, Manconi B, Olianas A, Sanna MT, Castagnola M, Messana I. Top-down analytical platforms for the characterization of the human salivary proteome. Bioanalysis. 2014; 6:563-81. Invited review (I.F. 3.027; Cit. 2; Q1)
  7. Incani F, Serra M, Meloni A, Cossu C, Saba L, Cabras T, Messana I, Rosatelli MC. AIRE acetylation and deacetylation: effect on protein stability and transactivation activity. J Biomed Sci. 2014; 21:85. (I.F. 2.736; Cit. 1; Q2)
  8. Iavarone F, D’Alessandro A, Tian N, Cabras T, Messana I, Helmerhorst EJ, Oppenheim FG, Castagnola M. High-resolution high-performance liquid chromatography with electrospray ionization mass spectrometry and tandem mass spectrometry characterization of a new isoform of human salivary acidic proline-rich proteins named Roma-Boston Ser(22)(Phos) -> Phe variant. J Sep Sci. 2014; 37(14):1896-902. (I.F. 2.594; Cit. 0; Q2)
  9. Iavarone F, Melis M, Platania G, Cabras T, Manconi B, Petruzzelli R, Cordaro M, Siracusano A, Faa G, Messana I, Zanasi M, Castagnola M. Characterization of salivary proteins of schizophrenic and bipolar disorder patients by top-down proteomics. J Proteomics. 2014; 103:15-22. (I.F. 3.929; Cit. 2; Q1)
  10. Theunissen W, Fanni D, Nemolato S, Di Felice E, Cabras T, Gerosa C, Van Eyken P, Messana I, Castagnola M, Faa G. Thymosin beta 4 and thymosin beta 10 expression in hepatocellular carcinoma. Eur J Histochem. 2014; 58(1):2242 (I.F. 2.237; Cit. 2; Q3)
  11. Nemolato S, Cabras T, Restivo A, Zorcolo L, Di Felice E, Fanni D, Gerosa C, Messana I, Castagnola M, Faa G, Casula G. Thymosin ß4 expression in colorectal polyps and adenomas. Clinics (Sao Paulo). 2013; 68:1220-4. (I.F. 1.422; Cit. 1; Q2)
  12. Manconi B, Cabras T, Pisano E, Sanna MT, Olianas A, Fanos V, Faa G, Nemolato S, Iavarone F, Castagnola M, Messana I. Modifications of the acidic soluble salivary proteome in human children from birth to the age of 48months investigated by a top-down HPLC-ESI-MS platform. J Proteomics. 2013; 91:536-43. (I.F. 3.929; Cit. 3; Q1)
  13. Cabras T, Iavarone F, Pirolli D, Cristina De Rosa M, Vitali A, Faa G, Cordaro M, Messana I, Ekström J, Castagnola M. Top-down HPLC-ESI-MS characterization of rat gliadoralin A, a new member of the family of rat submandibular gland glutamine-rich proteins and potential substrate of transglutaminase. J Sep Sci. 2013; 36:2848-61. (I.F. 2.594; Cit. 1; Q2)
  14. Pichiri G, Coni P, Nemolato S, Cabras T, Fanari MU, Sanna A, Di Felice E, Messana I, Castagnola M, Faa G. Cellular Trafficking of Thymosin Beta-4 in HEPG2 Cells Following Serum Starvation. PLoS One. 2013; 8:e67999. (I.F. 3.534; Cit. 0; Q1)
  15. Nemolato S, Ekstrom J, Cabras T, Gerosa C, Fanni D, Di Felice E, Locci A, Messana I, Castagnola M, Faa G. Immunoreactivity for thymosin beta 4 and thymosin beta 10 in the adult rat oro-gastro-intestinal tract. Eur J Histochem. 2013; 57:e17. (I.F. 2.237; Cit. 1; Q3)
  16. Cabras T, Pisano E, Montaldo C, Giuca MR, Iavarone F, Zampino G, Castagnola M, Messana I. Significant modifications of the salivary proteome potentially associated with complications of Down syndrome revealed by top-down proteomics. Mol Cell Proteomics. 2013; 12:1844-52. (I.F. 7.254; Cit. 9; Q1)
  17. Vento G, Lio A, Tirone C, Aurilia C, Tana M, Piras A, Ricci C, Perelli S, Romagnoli C, Posteraro B, Iavarone F, Cabras T, Fanali C, Messana I, Castagnola M. Association of high levels of α-defensins and S100A proteins with Candida mannan detection in bronchoalveolar lavage fluid of preterm neonates. Pediatr Res. 2013; 74:19-25. (I.F. 2.84; Cit. 1; Q1)
  18. Melis M, Aragoni MC, Arca M, Cabras T, Caltagirone C, Castagnola M, Crnjar R, Messana I, Tepper BJ, Barbarossa IT. Marked increase in PROP taste responsiveness following oral supplementation with selected salivary proteins or their related free amino acids. PLoS One. 2013; 8:e59810. (I.F. 3.534; Cit. 8; Q1)
  19. Chiusolo P, Giammarco S, Fanali C, Bellesi S, Metafuni E, Sica S, Iavarone F, Cabras T, Messana I, Leone G, Castagnola M. Salivary proteomic analysis and acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2013; 19:888-92. (I.F. 3.348; Cit. 2; Q2)
  20. Desiderio C, Martelli C, Rossetti DV, Di Rocco C, D’Angelo L, Caldarelli M, Tamburrini G, Iavarone F, Castagnola M, Messana I, Cabras T, Faa G. Identification of thymosins β4 and β 10 in paediatric craniopharyngioma cystic fluid. Childs Nerv Syst. 2013; 29:951-60. (I.F. 1.163; Cit. 3; Q3)
  21. Caboni P, Aissani N, Cabras T, Falqui A, Marotta R, Liori B, Ntalli N, Sarais G, Sasanelli N, Tocco G. Potent nematicidal activity of phthalaldehyde, salicylaldehyde, and cinnamic aldehyde against Meloidogyne incognita. J Agric Food Chem. 2013; 61:1794-803. (I.F. 3.107; Cit. 5; Q1)
  22. Castagnola M, Cabras T, Iavarone F, Fanali C, Messana I. Detection of Ca2+-binding S100 proteins in human saliva by HPLC-ESI-MS. Methods Mol Biol. (Clifton, N.J.) 2013; 963:357-71. (Cit. 1)
  23. Iavarone F, Cabras T, Pisano E, Sanna MT, Nemolato S, Vento G, Tirone C, Romagnoli C, Cordaro M, Fanos V, Faa G, Messana I, Castagnola M. Top-down HPLC-ESI-MS detection of S-glutathionylated and S-cysteinylated derivatives of cystatin B and its 1-53 and 54-98 fragments in whole saliva of human preterm newborns. J Proteome Res. 2013; 12:917-26. (I.F. 5.001; Cit. 4; Q1)
  24. Conti S, Radicioni G, Ciociola T, Longhi R, Polonelli L, Gatti R, Cabras T, Messana I, Castagnola M, Vitali A. Structural and functional studies on a proline-rich peptide isolated from swine saliva endowed with antifungal activity towards Cryptococcus neoformans. Biochim Biophys Acta. 2013; 1828:1066-74. (I.F. 3.431; Cit. 0; Q2)
  25. Messana I, Cabras T, Iavarone F, Vincenzoni F, Urbani A, Castagnola M. Unraveling the different proteomic platforms. J Sep Sci. 2013; 36:128-39. (I.F. 2.594; Cit. 10; Q2)
  26. Castagnola M, Cabras T, Iavarone F, Vincenzoni F, Vitali A, Pisano E, Nemolato S, Scarano E, Fiorita A, Vento G, Tirone C, Romagnoli C, Cordaro M, Paludetti G, Faa G, Messana I. Top-down platform for deciphering the human salivary proteome. J Matern Fetal Neonatal Med. 2012; 25:27-43. (I.F. 1.208; Cit. 8; Q4)
  27. Faa G, Nemolato S, Cabras T, Fanni D, Gerosa C, Fanari M, Locci A, Fanos V, Messana I, Castagnola M. Thymosin β4 expression reveals intriguing similarities between fetal and cancer cells. Ann N Y Acad Sci. 2012; 1269:53-60. (I.F. 4.039; Cit. 6; Q1)
  28. D’Amato F, Cocco C, Noli B, Cabras T, Messana I, Ferri GL. VGF peptides upon osmotic stimuli: Changes in neuroendocrine regulatory peptides 1 and 2 in the hypothalamic-pituitary-axis and plasma. J Chem Neuroanat. 2012; 44:57-65. (I.F. 2.52; Cit. 3; Q3)
  29. Cabras T, Boi R, Pisano E, Iavarone F, Fanali C, Nemolato S, Faa G, Castagnola M, Messana I. HPLC-ESI-MS and MS/MS structural characterization of multifucosylated N-glycoforms of the basic proline-rich protein IB-8a CON1+in human saliva . J Sep Sci. 2012; 35:1079-1086. (I.F. 2.594; Cit. 5; Q2)
  30. Cabras T, Manconi B, Iavarone F, Fanali C, Nemolato S, Fiorita A, Scarano E, Passali GC, Manni A, Cordaro M, Paludetti G, Faa G, Messana I, Castagnola M. RP-HPLC–ESI-MS evidenced that salivary cystatin B is detectable in adult human whole saliva mostly as S-modified derivatives: S-Glutathionyl, S-cysteinyl and S–S 2-mer. Journal of Proteomics. 2012; 75:908-13. (I.F. 3.929; Cit. 14; Q1)
  31. Nemolato S, Restivo A, Cabras T, Coni P, Zorcolo L, Fanari M, Orrù G, Cau F, Gerosa C, Fanni D, Messana I, Castagnola M, Casula G, Faa G. Thymosin beta 4 in colorectal cancer is localized predominantly at the invasion front in tumor cells undergoing epithelial mesenchymal transition. Cancer Biol Ther. 2012; 13:191-7 (I.F. 3.63; Cit. 10; Q2)
  32. Castagnola M, Cabras T, Iavarone F, Fanali C, Nemolato S, Peluso G, Laura Bosello SL, Faa G, Ferraccioli G, Messana I. The human salivary proteome: a critical overview of the results obtained by different proteomic platforms. Expert Revew of Proteomics. 2012; 9:33-46. (I.F. 3.542; Cit. 11; Q2)
  33. Cabras T, Melis M, Castagnola M, Padiglia A, Tepper BJ, Messana I, Tomassini Barbarossa I. Responsiveness to 6-n-propylthiouracil (PROP) is associated with salivary levels of two specific basic proline-rich proteins in humans. PLoS One. 2012; 7:e30962. (I.F. 3.534; Cit. 17; Q1)
  34. Castagnola M, Picciotti PM, Messana I, Fanali C, Fiorita A, Cabras T, Calò L, Pisano E, Passali GC, Iavarone F, Paludetti G, Scarano E. Potential applications of human saliva as diagnostic fluid. Acta Otorhinolaryngol Ital. 2011; 31:347-57. (I.F. 1.439; Cit. 25; Q2)
  35. Fanni D, Gerosa C, Nemolato S, Locci A, Marinelli V, Cabras T, Messana I, Fanos V, Castagnola M, Faa G. Thymosin beta 10 expression in developing human salivary glands. Early Hum Dev. 2011; 87:779-783. (I.F. 1.931; Cit. 4; Q2)
  36. Castagnola M, Cabras T, Vitali A, Sanna MT, Messana I. Biotechnological implications of the salivary proteome. Trends Biotechnol. 2011; 29:409-18. Invited Review. (I.F. 10.04; Cit. 24; Q1)
  37. De Santis M, Inzitari R, Bosello SL, Peluso G, Fanali C, Iavarone F, Zizzo G, Bocci M, Cabras T, Messana I, Fuso L, Varone F, Pagliari G, Castagnola M, Ferraccioli G. β-Thymosins and interstitial lung disease: study of a scleroderma cohort with a one-year follow-up. Respir Res. 2011; 12:22, doi:10.1186/1465-9921-12-22. (I.F. 3.382; Cit. 7; Q2)
  38. Nemolato S, Van Eyken P, Cabras T, Cau F, Fanari MU, Locci A, Fanni D, Gerosa C, Messana I, Castagnola M, Faa G. Expression pattern of thymosin beta 4 in the adult human liver. Eur J Histochem. 2011; 55:e25, 131-5. (I.F. 2.237; Cit. 6; Q3)
  39. Castagnola M, Inzitari R, Fanali C, Iavarone F, Vitali A, Desiderio C, Vento G, Tirone C, Romagnoli C, Cabras T, Manconi B, Sanna MT, Boi R, Pisano E, Olianas A, Pellegrini M, Nemolato S, Heizmann CW, Faa G, Messana I. The surprising composition of the salivary proteome of preterm human newborn. Mol Cell Proteomics. 2011; 10: 10.1074/mcp.M110.003467, 1–14. (I.F. 7.254; Cit. 23; Q1)
  40. Pettorini BL, Inzitari R, Massimi L, Tamburrini G, Caldarelli M, Fanali C, Cabras T, Messana I, Castagnola M, Di Rocco C. The role of inflammation in the genesis of the cystic component of craniopharyngiomas. Childs Nerv Syst. 2010; 26:1779-84. (I.F. 1.163; Cit. 4; Q3)
  41. Nemolato S, Cabras T, Fanari MU, Cau F, Fanni D, Gerosa C, Manconi B, Messana I, Castagnola M, Faa G. Immunoreactivity of thymosin beta 4 in human foetal and adult genitourinary tract. Eur J Histochem. 2010; 54:e43,193-6. (I.F. 2.237; Cit. 7; Q3)
  42. Gerosa C, Fanni D, Nemolato S, Locci A, Marinelli V, Cabras T, Messana I, Castagnola M, Monga G, Fanos V, Faa G. Thymosin beta-10 expression in developing human kidney. J Matern Fetal Neonatal Med. 2010; 23 Suppl 3:125-8. (I.F. 1.208; Cit. 7; Q4)
  43. Faa G, Gerosa C, Fanni D, Nemolato S, Locci A, Cabras T, Marinelli V, Puddu M, Zaffanello M, Monga G, Fanos V. Marked interindividual variability in renal maturation of preterm infants: lessons from autopsy. J Matern Fetal Neonatal Med. 2010; 23 Suppl 3:129-33. (I.F. 1.208; Cit. 26; Q4)
  44. Cabras T, Pisano E, Mastinu A, Denotti G, Pusceddu PP, Inzitari R, Fanali C, Nemolato S, Castagnola M, Messana I. Alterations of the salivary secretory peptidome profile in children affected by type 1 diabetes. Mol Cell Proteomics. 2010; 9:2099-108. (I.F. 7.254; Cit. 28; Q1)
  45. Tirone C, Boccacci S, Inzitari R, Tana M, Aurilia C, Fanali C, Cabras T, Messana I, Castagnola M, Romagnoli C, Vento G. Correlation of levels of alpha-defensins determined by HPLC-ESI-MS in bronchoalveolar lavage fluid with the diagnosis of pneumonia in premature neonates. Pediatr Res. 2010; 68:140-4. (I.F. 2.84; Cit. 2; Q1)
  46. Manconi B, Cabras T, Pisano E, Nemolato S, Inzitari R, Iavarone F, Fanali C, Sanna MT, Tirone C, Vento G, Romagnoli C, Faa G, Castagnola M, Messana I. Characterization of two isoforms of human SPRR3 from saliva of preterm human newborn and autoptic fetal oral mucosa, parotid and submandibular gland samples. Biochem Bioph Res Commun. 2010; 398:477-81. (I.F. 2.281; Cit. 4; Q3)
  47. Scarano E, Fiorita A, Picciotti PM, Passali GC, Calò L, Cabras T, Inzitari R, Fanali C, Messana I, Castagnola M, Paludetti G. Proteomics of saliva: personal experience. Acta Otorhinolaryngol Ital. 2010; 30:125-30. (I.F. 1.439; Cit. 16; Q2)
  48. Manconi B, Fanali C, Cabras T, Inzitari R, Patamia M, Scarano E, Fiorita A, Vitali A, Castagnola M, Messana I, Sanna MT. Structural characterization of a new statherin from pig parotid granules. J Pept Sci. 2010; 16:269-75. (I.F. 1.862; Cit. 2; Q3)
  49. Nemolato S, Cabras T, Cau F, Fanari MU, Fanni D, Manconi B, Messana I, Castagnola M, Faa G. Different thymosin Beta 4 immunoreactivity in foetal and adult gastrointestinal tract. PLoS One. 2010; 5:e9111. (I.F. 3.534; Cit. 12; Q1)
  50. Nemolato S, Cabras T, Fanari MU, Cau F, Fraschini M, Manconi B, Messana I, Castagnola M, Faa G. Thymosin beta 4 expression in normal skin, colon mucosa and in tumor infiltrating mast cells. Eur J Histochem. 2010; 54:e3, 14-17. (I.F. 2.237; Cit. 7; Q3)
  51. Manconi B, Cabras T, Vitali A, Fanali C, Fiorita A, Inzitari R, Castagnola M, Messana I, Sanna MT. Expression, purification, phosphorylation and characterization of recombinant human statherin. Protein Expr Purif, 2010; 69:219-25. (I.F. 1.508; Cit. 2; Q3)
  52. Ekström J, Murakami M, Inzitari R, Khosravani N, Fanali C, Cabras T, Fujita-Yoshigaki J, Sugiya H, Messana I, Castagnola M. RP-HPLC-ESI-MS characterization of novel peptide fragments related to rat parotid secretory protein in parasympathetic induced saliva. J Sep Sci. 2009; 32:2944-52. (I.F. 2.594; Cit. 2; Q2)
  53. Cabras T, Pisano E, Boi R, Olianas A, Manconi B, Inzitari R, Fanali C, Giardina B, Castagnola M, Messana I. Age-dependent modifications of the human salivary secretory protein complex. J Proteome Res. 2009; 8:4126-34. (I.F. 5.001; Cit. 25; Q1)
  54. Inzitari R, Cabras T, Pisano E, Fanali C, Manconi B, Scarano E, Fiorita A, Paludetti G, Manni A, Nemolato S, Faa G, Castagnola M, Messana I. HPLC-ESI-MS analysis of oral human fluids reveals that gingival crevicular fluid is the main source of oral thymosins beta(4) and beta(10). J Sep Sci. 2009; 32:57-63. (I.F. 2.594; Cit. 29; Q2)
  55. Nemolato S, Messana I, Cabras T, Manconi B, Inzitari R, Fanali C, Vento G, Tirone C, Romagnoli C, Riva A, Fanni D, Di Felice E, Faa G, Castagnola M. Thymosin beta(4) and beta(10) levels in pre-term newborn oral cavity and foetal salivary glands evidence a switch of secretion during foetal development. PLoS One. 2009; 4:e5109. (I.F. 3.534; Cit. 27; Q1)
  56. Castagnola M, Messana I, Inzitari R, Fanali C, Cabras T, Morelli A, Pecoraro AM, Neri G, Torrioli MG, Gurrieri F. Hypo-phosphorylation of salivary peptidome as a clue to the molecular pathogenesis of autism spectrum disorders. J Proteome Res. 2008; 7:5327-32. (I.F. 5.001; Cit. 30; Q1)
  57. Cabras T, Castagnola M, Inzitari R, Ekström J, Isola M, Riva A, Messana I. Carbachol-induced in vitro secretion of certain human submandibular proteins investigated by mass-spectrometry. Arch Oral Biol. 2008; 53:1077-83. (I.F. 1.88; Cit. 2; Q2)
  58. Fanali C, Inzitari R, Cabras T, Pisano E, Castagnola M, Celletti R, Manni A, Messana I. alpha-Defensin levels in whole saliva of totally edentulous subjects. Int J Immunopathol Pharmacol. 2008; 21:845-9. (I.F. 2.507; Cit. 11; Q2)
  59. Messana I, Inzitari R, Fanali C, Cabras T, Castagnola M. Facts and artifacts in proteomics of body fluids. What proteomics of saliva is telling us? J Sep Sci. 2008; 31:1948-63. Review. (I.F. 2.594; Cit. 57; Q2)
  60. Rigante D, Inzitari R, Carone M, Fanali C, Stabile A, Cabras T, Capoluongo E, Gaspari S, Barone G, Castagnola M. Correspondence between clinical improvement and proteomic changes of the salivary peptide complex in a child with primary Sjögren syndrome. Rheumatol Int. 2008; 28:801-6. (I.F. 1.627; Cit. 6; Q3)
  61. Isola M, Cabras T, Inzitari R, Lantini MS, Proto E, Cossu M, Riva A. Electron microscopic detection of statherin in secretory granules of human major salivary glands. J Anat. 2008; 212:664-8. (I.F. 2.227; Cit. 7; Q1)
  62. Messana I, Cabras T, Pisano E, Sanna MT, Olianas A, Manconi B, Pellegrini M, Paludetti G, Scarano E, Fiorita A, Agostino S, Contucci AM, Calò L, Picciotti PM, Manni A, Bennick A, Vitali A, Fanali C, Inzitari R, Castagnola M. Trafficking and postsecretory events responsible for the formation of secreted human salivary peptides: a proteomics approach. Mol Cell Proteomics. 2008; 7:911-26. (I.F. 7.254; Cit. 51; Q1)
  63. Cabras T, Longhi R, Secundo F, Nocca G, Conti S, Polonelli L, Fanali C, Inzitari R, Petruzzelli R, Messana I, Castagnola M, Vitali A. Structural and functional characterization of the porcine proline-rich antifungal peptide SP-B isolated from salivary gland granules. J Pept Sci. 2008; 14:251-60. (I.F. 1.862; Cit. 12; Q3)
  64. Fanali C, Inzitari R, Cabras T, Fiorita A, Scarano E, Patamia M, Retruzzelli R, Bennick A, Messana I, Castagnola M. Mass spectrometry strategies applied to the characterization of proline-rich peptides from secretory parotid granules of pig (Sus scrofa). J Sep Sci. 2008; 31:516-22. (I.F. 2.594; Cit. 6; Q2)
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